The effect of decaffeination of coffee on gastro-oesophageal reflux in patients with reflux disease

Effect of atropine on gastro-oesophageal reflux and transient lower oesophageal sphincter relaxations in patients with gastro-oesophageal reflux disease.

BACKGROUND Atropine reduces the rate of reflux episodes in normal subjects by inhibition of transient lower oesophageal sphincter (LOS) relaxations. The aim of this study was to investigate the effect of atropine on the rate and mechanisms of reflux in patients with reflux disease. METHODS Oesophageal motility and pH were recorded for one hour after a meal in 15 patients with reflux disease. ...

GASTRO-OESOPHAGEAL REFLUX Mechanisms of gastro-oesophageal reflux in preterm and term infants with reflux disease

Background: Transient lower oesophageal sphincter relaxation (TLOSR) is the predominant mechanism of gastro-oesophageal reflux (GOR) in healthy infants but the mechanisms of GOR in infants with GOR disease (GORD) are poorly understood. Aims: To measure the occurrence of TLOSR, GOR, and gastric emptying (GE) rate in preterm and term infants with GORD. Patients: Thirty six infants were studied an...

Gastro-oesophageal Reflux Disease

Gastro-oesophageal Reflux Disease

Gastro-oesophageal reflux disease.

Accepted for publication 25 March 1991 Abstract Recent studies suggest that vagal nerve dysfunction may be important in the aetiology of gastro-oesophageal reflux disease. Delayed oesophageal transit and slowed gastric emptying occur frequently and may also be of pathogenic importance. In 48 patients with gastro-oesophageal reflux disease we studied the prevalence of and relations between auton...